Updated August 10, 2026

20 open positions

Clinical Operations Jobs with a Great Work-Life Balance

Browse 20+ clinical operations jobs at companies offering generous PTO and unlimited PTO—full pay and a better work-life balance. 15 new this week. Hiring companies include Genentech, Sanofi, and Spring Health.

Jobs

New This Week

10+

Companies

Updated Daily

Lead Clinical Care Navigator

Spring Health

RemoteEurope or Asia

62 · Good5 day weekUnlimited PTO$80k – $92k

Associate Director, Clinical Trial Lead

Biogen

RemoteUSA

60 · Good5 day weekGenerous PTO

Clinical Transformation Lead

Clarium

RemoteUSA

61 · Good5 day weekUnlimited PTO$140k – $180k

Senior Market Operations Program Manager

18d

Clover Health

RemoteUSA

63 · Good5 day weekUnlimited PTO$107k – $140k

Senior Clinical Quality Manager, AI Transformation

1mo

Spring Health

RemoteUSA

62 · Good5 day weekUnlimited PTO$122k – $140k

Clinical Research Engagement Lead - South Region

Genentech

HybridAtlanta, USA

60 · Good5 day weekGenerous PTO$109k – $202k

Clinical Research Engagement Lead - South Region

Genentech

HybridJacksonville, USA

60 · Good5 day weekGenerous PTO$109k – $202k

Clinical Research Engagement Lead - South Region

Genentech

HybridNashville, USA

60 · Good5 day weekGenerous PTO$109k – $202k

Business Intelligence Engineer

Merck

HybridMunro, Argentina

59 · Good5 day weekGenerous PTO

Regulatory Affairs Operations Manager

University of Washington

HybridSeattle, USA

61 · GoodCompressed week$120k – $174k

Local Study Operations Senior Manager

Amgen

HybridIstanbul, Turkey

59 · Good5 day weekGenerous PTO

Associate Director, Country Site & Operations FSP Oversight Manager

Biogen

HybridBaar, Switzerland

60 · Good5 day weekGenerous PTO

Executive Medical Director, Clinical Development- Immunology

Vertex Pharmaceuticals

HybridBoston, USA

59 · Good5 day weekGenerous PTO

Clinical Operations Study Country Lead

Sanofi

HybridShanghai, China

59 · Good5 day weekGenerous PTO

Clinical Quality Program Consultant - Radiology

12d

Ohio State University

OnsiteColumbus, USA

61 · GoodCompressed week

R&D Clinical Trial Support Manager

19d

Sanofi

HybridHyderabad, India

59 · Good5 day weekGenerous PTO

Clinical Research Engagement Lead - South Region

Genentech

HybridMiami, USA

60 · Good5 day weekGenerous PTO$109k – $202k

Clinical Research Engagement Lead

Genentech

HybridOrlando, USA

60 · Good5 day weekGenerous PTO$109k – $202k

Clinical Research Engagement Lead (CREL) - Central Region

Genentech

HybridNew Orleans, USA

60 · Good5 day weekGenerous PTO$103k – $192k

Clinical Research Engagement Lead - West Region

Genentech

HybridSouth San Francisco, USA

60 · Good5 day weekGenerous PTO$125k – $232k

Every role is a genuine reduced-hours position, manually curated and refreshed daily. How we curate

Got questions?

Frequently asked questions

Everything you need to know about 4-day week jobs

Employers hiring for Clinical Operations on this page include Genentech, Sanofi, and Spring Health. Clinical Operations roles appear most frequently in engineering, data, and platform teams at companies that have adopted a reduced-hours schedule. Each listing indicates the seniority level and whether Clinical Operations is a primary requirement or one of several preferred skills — expand any role above to see the full stack and responsibilities.

Clinical Operations roles span the full seniority range — we list 20 open roles requiring Clinical Operations across entry-level, mid-level, senior, lead, and staff/principal positions. Senior and above tend to dominate because employers offering reduced-hours schedules often lean toward experienced individual contributors who can deliver consistently in fewer hours. Filter by level in the sidebar to narrow the list above.

Lead with measurable outcomes over time spent — Clinical Operations hiring managers at reduced-hours companies care about delivered value, not hours worked. Highlight projects where you shipped at a steady cadence, collaborated asynchronously, or reduced engineering toil through automation or tooling. Include concrete metrics (latency improvements, adoption numbers, cost reductions) rather than vague duty descriptions. Expand listings above to see the exact framing each employer uses in their job descriptions.

For the full-pay schedules here — 4-day weeks and 9-day fortnights — yes: you keep a full-time salary for a shorter week. Part-time and pro-rata roles instead scale pay to hours, and each listing makes the arrangement clear. Clinical Operations roles in tech and data typically command premium rates at both reduced-hours and traditional employers; specific ranges depend on seniority, location, and sub-specialty (e.g. backend vs frontend, infra vs ML). Individual listings above show exact bands where the employer publishes them.

Depends on the role, but Clinical Operations candidates who also demonstrate async communication, clean documentation, and cross-functional collaboration are typically strong fits for reduced-hours employers — those companies rely on written-first communication and high-context handoffs to operate on a compressed schedule. Technical-adjacent skills vary by stack. Browse the top skills shown in the sidebar to see which tags co-occur most often with Clinical Operations on current listings.