About CRIO
What is CRIO?
CRIO (Clinical Research IO) builds the electronic source (eSource) and site-management platform that thousands of clinical research sites use to run drug trials — replacing the paper binders that still dominate clinical data capture with structured, compliant, real-time electronic workflows. Founded in Boston in 2015, CRIO serves research sites, site networks, sponsors and CROs; its system handles everything from eConsent and eRegulatory to CTMS-style scheduling and finance. It is a healthcare software company: the people it hires build and sell the platform — there are no patient-facing clinical roles on its board.
Where will I work?
Anywhere. CRIO's roles are fully remote across the US ("Work from anywhere" is the first line of its benefits list; most roles ask only for availability on Eastern Time). The company is headquartered in Boston, Massachusetts. The clinical-research market it serves is structurally growing — decentralised and hybrid trials keep pushing sites off paper — which gives CRIO the rare combination of a mission-adjacent product and a durable commercial tailwind.
What is the CRIO team like?
Around 150 people across engineering, product, sales, marketing and customer experience. Reviewers on Glassdoor rate CRIO 4.7 overall, with leadership praised specifically for cutting meeting load and genuinely honouring flexible time off — the culture the policy claims to describe. CRIO's platform now spans eSource data capture, eConsent, eRegulatory document management, scheduling, and payments — an end-to-end operating system for a research site — and the company has taken private-equity growth investment (~$21M) to keep extending it. Interviews run through a straightforward Rippling pipeline, and most roles simply ask for availability on US Eastern hours.
Work-Life Balance
"Unlimited PTO" appears verbatim in eight of CRIO's nine live job descriptions, across every function from engineering to sales — it is the company-wide policy, not a perk for one team. Combined with work-from-anywhere remote and a 4.7 Glassdoor rating, this is one of the stronger trust-based-PTO setups we list.
Perks and Benefits
- "Unlimited PTO" — verbatim, company-wide (8/9 live JDs)
- "Work from anywhere" — fully remote US
- "401k company match"
- "Healthcare / Dental / Vision (Company Paid 100%)"
- "Life insurance"
- "Professional development" budget and "Work From Home Expense Reimbursement"